Recently, the estimation of joint kinetics such as joint force and moment using wearable inertial sensors has received great attention in biomechanics. Generally, the joint force and moment are calculated though inverse dynamics using segment kinematic data, ground reaction force, and moment. However, this approach has problems such as estimation error of kinematic data and soft tissue artifacts, which can lead to inaccuracy of joint forces and moments in inverse dynamics. This study aimed to apply a recurrent neural network (RNN) instead of inverse dynamics to joint force and moment estimation. The proposed RNN could receive signals from inertial sensors and force plate as input vector and output lower extremity joints forces and moments. As the proposed method does not depend on inverse dynamics, it is independent of the inaccuracy problem of the conventional method. Experimental results showed that the estimation performance of hip joint moment of the proposed RNN was improved by 66.4% compared to that of the inverse dynamics-based method.