The bone scaffold is artificial mechanical support, that is implanted on collapsed bone microstructure. The clinical field has become interested in that, because it is free of immunological rejection. However, few studies have analyzed quantitively the mechanical interaction with the surrounding bone tissue, when the bone scaffold is implanted. Thus, the purpose of this study was to analyze structural behavior variance, according to porous structures of the bone scaffold. This study set the proximal femoral head as the implantation skeletal system, and defined bone scaffolds (i.e. triangular, rectangle, circular, honeycomb) with four porous structures. Then, structural behavior variance was analyzed, caused by the implantation of bone scaffolds. As a result, it was quantitatively confirmed that a porous structure such as a normal bone that can transmit and support an external load is important.