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"용매 추출 공정"

Article
Evaluation of the Manufacturing and Viral Killing Efficacy of Chitosan Microbeads Loaded with Disinfectants
Bong Su Kang, Sung Hak Choi, Moon Kyu Kwak, Ho-Sup Jung
J. Korean Soc. Precis. Eng. 2024;41(7):507-513.
Published online July 1, 2024
DOI: https://doi.org/10.7736/JKSPE.024.045
This study examines the efficiency of chitosan microbeads in manufacturing and their effectiveness as a disinfectant. The microbeads are developed using a solvent-assisted extraction process. The manufacturing process involves crosslinking chitosan through an emulsion-based method, with the help of a crosslinker. This leads to an increase in particle size while maintaining homogeneity and dispersion. The solvent-assisted method, which utilizes acetone, effectively extracts the crosslinked beads into the aqueous phase. This extraction process ensures the structural stability of the beads, with an average particle size of 40±3.94 ㎛. By incorporating the disinfectant agent into the chitosan beads, antiviral effects against the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) were observed. These effects were found to be effective at dilutions estimated to be between 1 : 1 and 1 : 100. The findings of this study demonstrate the inherent antiviral capabilities of chitosan beads and the enhanced impact when combined with the disinfectant. This suggests a synergistic approach to managing viral infections in livestock environments.
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