An optimal design was developed for housing of a 50-ton hydraulic breaker. A four-factor, two-level design was created using the full factorial design, and it was confirmed that the safety factor, the response value, exhibited a curvature. As the curvature was confirmed, a higher-order experiment, a response surface analysis was performed. Based on the Minitab"s optimized prediction of the safety factor and weight, the actual analysis was performed using ANSYS Workbench, the finite element analysis program. As a result, the safety factor was 2.03 and the weight was 3222.2 kg, which was almost consistent with the Minitab’s prediction. The safety factor decreased from 2.33 to 2.03 compared to that in the initial model, but the optimization model can also be judged as being safe because the safety factor was set to 2.00. The weight was reduced by 119.1 kg, from 3341.3 to 3222.2 kg.