Bone plates made of biodegradable polymers have been used to fix broken bones. 3D printers are used to produce the bone plates for fracture fixing in the industry. The dimensional accuracy of the product printed by a 3D printer is less than 80%. Fracture fixing plates with less than 80% dimensional accuracy cause problems during surgery. There is an urgent need to improve the dimensional accuracy of the product in the industry. In this paper, a methodology using machine learning was proposed to improve the dimensional accuracy. The proposed methodology was evaluated through case studies. The results predicted by the machine learning methodology proposed in this paper and the experimental results were compared through the experiment. After verification, results of the proposed prediction model and the experimental results were in good agreement with each other.