This paper proposes a myoelectric hand prosthesis with an easy control strategy to apply more conveniently with just two EMG sensors. The myoelectric hand prosthesis is composed of a multi-DOF finger mechanism, a controller, and an intuitive control algorithm. The developed hand prosthesis has 6-DOFs and can perform eight hand motions using the intuitive control algorithm. The proposed intuitive control algorithm classifies four grip motions and four gesture motions; we used the thumb position of the hand prosthesis and three EMG signals (Co-contraction, flexion, and extension) generated from the two EMG sensors. From the experimental results, we demonstrated that the proposed myoelectric hand prosthesis is applicable to amputees as a hand prosthesis.