Crash analyses was carried out to characterize crash behavior and injury of a wheelchair user in a train during collision based on SAFETRAIN PROJECT and AV/ST 9001, train safety regulations. There is no restraint system such as seat belt or air-bag in train, a wheelchair user is normally injured by bumping against wall. Crash behavior and injury of a wheelchair user was evaluated with respect to the distance (Dw) of the wheelchair from the wall and the wall foam thickness (tF). Additional crash analysis for a wheelchair user with seat belt was also performed in order to check the significance of the seat belt effect during crash.