Recently, competition in the manufacturing industry related to the preoccupation of new markets has drastically changed due to the increase in small quantity batch production products. Besides, business models utilizing 3D printing technology suitable for flexible manufacturing are gaining interest. As 3D printing technology is becoming more common, Design for Additive Manufacturing is also in the spotlight. However, the productivity of 3D printing technology is still insufficient in terms of mass production. In this study, the possibility of innovation in mass production process that combines 3D printing technology is presented through the case of innovation in manufacturing productivity of medium-speed engine cylinder head through the integration of sand 3D printing technology. It outlines how sand 3D printing technology is applied to cylinder head mass production processes, how the quality of cylinder head products can be improved compared to conventional pattern-based molding methods, and how productivity can be maximized by reducing process time and human error through hybrid production method with sand 3D printed integrated design cores. In conclusion, this paper presents the effectiveness of sand 3D printing technology which can secure product competitiveness by increasing the production capacity of mass production process, reducing production costs, improving quality, and reducing loss.