With recent development of 3D printing technology, its applications to the bio-industry are increasing. Many research studies are being done for manufacturing personalized tablets through this technology in the pharmaceutical process. In this study, to control the dissolution rate of tablets, a lattice structure was inserted into the tablet and the dissolution rate was compared. The tablet proposed in this study can be manufactured by the FDM method, adopting a lattice structure with a large surface area-to-volume ratio. Tablets containing various lattice structures were fabricated using water-soluble PVA filaments and dissolution experiments were conducted in water at 37oC. As a result, it was confirmed that the specific surface area and the mass loss rate were proportional to both the 3D lattice structure and the monolith structure. Among different structures, the diamond structure had the most active dissolution.