Urban air mobility (UAM) is rapidly growing as a new means of transportation. As a result, noise pollution is emerging as a new technical challenge. Therefore, the sawtooth-shaped biomimetic designs were incorporated on the trailing edge of the blade to reduce flow-induced noise. The biomimetic virtual design was analyzed using the CFD software, ANSYS FLUENT V20.2. Based on the steady-state RANS flow solution, the acoustic power was calculated using the broadband noise source model to evaluate acoustic radiation. Four different cases with cutting lengths of 3.1 mm, 3.7 mm, 4.3 mm, and 4.9 mm of blades were compared with the base model at the rotational blade speed of 6,000 RPM. The maximum acoustic power level of the biomimetic blades ranged from 37.24 dB to 39.88 dB, resulting in a 10% reduction compared to the original blade (42.02 dB). The novel design affected the blade area, which inevitably reduced the slight thrust performance. However, the thrust was reduced to approximately less than 5% compared with the base blade in case 1. The biomimetic blade reduced the thrust due to its aerodynamic characteristics. However, the design of a blade with an appropriate cutting length has a greater effect in reducing noise rather than thrust.