There is a certain limit to reproduce phenomena between the real vehicle and road, since the existing methods to verify durability of the wheel are mostly uni-axial tests. And the change of durability of the wheel can’t be predicted since these tests don’t consider the camber angle and lateral force as important factors. In this paper, the FE models of the wheel-tire and drum are created. Then, the vertical and lateral loads are applied to wheel-tire assembly and the camber angle is applied by inclining the wheel-tire assembly to the drum. Based on the analysis result, the crack position is predicted to be created in the body of the wheel. The variation of the stress according to the camber angle is verified and the maximum spot of the stress changes continually.