Korea’s first Naro-Science small class satellite was launched by Naro launcher in 2013. The structure of the satellite is mostly composed of aluminum honeycomb and frame. The honeycomb structure is homogenized with asymptotic homogenization method and its mechanical properties were used for the numerical analysis. There have been some difficulties to modeling the honeycomb sandwich panels for FEA. In the present study, the mechanical characteristics of the sandwich panel composite were numerically computed and used for the simulation. This methodology makes it easy to overcome the weakness of modeling of complicated sandwich panels. Both an experiment of vibration test and numerical analyses were conducted simultaneously. The analysis results from the current homogenization were compared with that of experiment. It shows a good agreement on the dynamic responses and certified the reliability of the present methodology when manipulate sandwich panel structure.