A roll-to-roll (R2R) continuous manufacturing system for a carbon-nanotube (CNT)-/silvernanowire (AgNW)- based large-area transparent conductive film was introduced in this study. The systemic guidelines of the R2R slot-die coating process including roll eccentricity, wrap angle, pump accuracy, and blower influence were discussed. To simulate the coating phenomenon, we investigated the governing parameters of the coating process by incorporating the estimated relative thickness that was defined by combining the viscocapillary model and volume model. By using experimental and mathematical approaches, an excellent transparent conductive layer with a 40 Ω/□ sheet resistance and 88 % transmittance was obtained; moreover, a dimensionless number identifies the correlation between the transparent conductive film and the anti-reflection film.